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奥西替尼主要针对肺癌EGFR常见敏感突变服用一代TKI(络氨酸抑制剂)后出现T790M突变的非小细胞肺癌患者的治疗,在美国奥西替尼被批准作为一线治疗非小细胞肺癌,也就是无论是否出现T790M突变,都可以用奥西替尼奥西替尼抑制,并且奥西替尼临床效果优于一代TKI。